![]() pharmacopoeia in 1820 ( Park and Lee 2006) and was clinically used in the 1930s for the treatment of radiotherapy burns to the skin and mucous membranes ( Collins and Collins 1935 Manderville 1939). Aloe vera was officially listed as a purgative and skin protectant by the U.S. The Aloe vera plant is described in detail in the Greek Herbal of Dioscorides (ca 70 ad), and its use promoted for the treatment of wounds, hair loss, genital ulcers, and hemorrhoids ( Davis 1997). However, the first detailed depiction of the plant’s medicinal value is found in the Papyrus Ebers, an Egyptian document dated at ca 1550 bce, which sets out multiple Aloe-containing preparations for the treatment of external and internal ailments. The first authentic record of Aloe as a plant with healing properties is accredited to a Mesopotamian clay tablet dated at ca 2100 bce. The geographic origin of Aloe vera is believed to be in Sudan, with the plant subsequently being introduced in the Mediterranean region and most other warm areas of the world ( Grindlay and Reynolds 1986).Īloe has been used extensively by the Egyptians, Assyrians, Mediterranean civilizations and in Biblical times ( Grindlay and Reynolds 1986). Commonly known as Aloe barbadensis Miller, its legitimate name according to the international rules of botanical nomenclature is A. 2000), which is variously classified as belonging to the Asphodelaceae, Liliaceae, or Aloaceae families. The conditions for which clinical trials of Aloe vera have been conducted include skin conditions, management of burn and wound healing, constipation, DM, and gastrointestinal disorders.Īloe vera is one of approximately 420 species of the genus Aloe ( Dagne et al. In the case of health, the therapeutic claims for the topical and oral application of Aloe vera cover a wide range of conditions, but few claims have been the subject of robust clinical investigation. In Western society, Aloe vera is one of the few herbal medicines in common usage, and it has found widespread use in the cosmetic, pharmaceutical, and food industries. ![]() In Chinese medicine, it is often recommended in the treatment of fungal diseases ( Heber 2007). It is also used in Trinidad and Tobago for hypertension ( Lans 2006) and among Mexican Americans for the treatment of type 2 diabetes mellitus (DM Coronado et al. It is used in traditional Indian medicine for constipation, colic, skin diseases, worm infestation, and infections ( Heber 2007). Aloe vera has a long history of popular and traditional use.
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